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Data source: VAERS (Vaccine Adverse Event Reporting System)

Data through 2026 · Updated quarterly

Built by TheDataProject.ai · © 2026 VaccineWatch

Important: VAERS accepts reports of adverse events following vaccination. For any given report, there is no certainty that the reported event was caused by the vaccine. Reports may contain information that is incomplete, inaccurate, coincidental, or unverifiable. Most reports to VAERS are voluntary, which means they are subject to biases. This data cannot be used to determine if vaccines cause or contribute to adverse events.

⚠️

Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.

  1. Home
  2. Vaccine Side Effects
  3. HPV Vaccine
7 min read
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HPV Vaccine Side Effects

The HPV (human papillomavirus) vaccine prevents cancers caused by HPV, including cervical, throat, and anal cancers. HPV vaccines have been the subject of significant public debate, making transparent data access especially important.

72,946
Total Reports
551
Deaths Reported
3,504
Hospitalizations
19,356
ER Visits

Most Commonly Reported Side Effects

The following symptoms are most frequently reported after vaccination:

#{i + 1}No adverse event
6,896
#{i + 1}Syncope
6,607
#{i + 1}Dizziness
6,600
#{i + 1}Headache
5,447
#{i + 1}Nausea
4,328
#{i + 1}Pyrexia
3,246
#{i + 1}Fatigue
3,179
#{i + 1}Loss of consciousness
3,104
#{i + 1}Pain
2,740
#{i + 1}Incorrect product storage
2,638
#{i + 1}Pain in extremity
2,621
#{i + 1}Vomiting
2,614

HPV Vaccine Versions

  • Gardasil (HPV4): Original quadrivalent vaccine — 4 HPV types
  • Gardasil 9 (HPV9): Current version — 9 HPV types, broader protection
  • Cervarix (HPV2): Bivalent, no longer available in the U.S.

Expected Side Effects

Common:

  • Pain, redness, or swelling at injection site (very common)
  • Fainting/syncope (more common in adolescents — 15-minute observation recommended)
  • Headache
  • Nausea
  • Dizziness
  • Fever

Rare but reported:

  • Allergic reactions
  • Blood clots (extremely rare, not clearly linked to vaccine)
  • Guillain-Barré Syndrome (studied extensively, no confirmed link)

The Fainting Factor

HPV vaccination has higher reported rates of syncope (fainting) than most vaccines. This is likely because the vaccine is given to adolescents, who are more prone to vasovagal responses. The CDC recommends a 15-minute observation period after HPV vaccination. Many VAERS reports for HPV are fainting-related rather than indicating serious adverse effects.

HPV vaccination is routinely recommended starting at ages 11-12. See where it fits on the CDC vaccine schedule and our 2026 vaccine schedule analysis.

⚠️ Remember: VAERS reports show correlation, not causation. A report filed after vaccination doesn't mean the vaccine caused the reported event. Always consult your healthcare provider for medical advice.

Explore This Data

Gardasil (HPV4) Detail →
Full VAERS profile
Gardasil 9 (HPV9) Detail →
Current HPV vaccine data
Age Patterns Analysis →
How age affects reporting

2026 Safety Monitoring Update

As of mid-2026, the HPV vaccine continues to be monitored through VAERS and complementary surveillance systems including the Vaccine Safety Datalink (VSD) and the Clinical Immunization Safety Assessment (CISA) project. No new safety signals have been identified in recent data that would change the established safety profile of this vaccine.

The HHS administration's announced development of AI-powered VAERS analysis tools may provide additional insights into HPV vaccine adverse event patterns. These tools aim to detect subtle signals that traditional statistical methods might miss, though their implementation timeline and methodology remain under development.

It's worth noting that VAERS reporting for routine vaccines like HPV has remained stable through the post-pandemic period. While COVID-19 vaccine reports surged and then declined, reporting patterns for established childhood and adult vaccines have been remarkably consistent, suggesting that the VAERS system continues to function as designed for ongoing safety surveillance.

Understanding VAERS Data for HPV

When interpreting VAERS data for HPV vaccines, several key principles apply:

  • Reports ≠ Causation: A VAERS report means an event occurred after vaccination. It does not establish that the vaccine caused the event. Many reported symptoms are common health occurrences that would happen regardless of vaccination.
  • No denominator: VAERS does not track the number of doses administered. Without knowing how many people received the vaccine, raw report counts cannot be used to calculate risk rates or compare safety across vaccines.
  • Co-administration: Many vaccines are given at the same visit. When a VAERS report lists multiple vaccines, it's impossible to determine which vaccine (if any) was responsible for the reported adverse event.
  • Reporting variability: Healthcare provider awareness, media attention, and public concern all influence how many reports are filed. Changes in report volume may reflect changes in reporting behavior rather than changes in actual safety.

How to Use This Data Responsibly

VAERS data is most useful as a starting point for conversation with your healthcare provider, not as a basis for medical decisions. If you're concerned about HPV vaccine side effects:

  • Discuss your specific risk factors with your doctor or pharmacist
  • Ask about the relative risks of the disease the vaccine prevents vs. the vaccine itself
  • Consider your age, health status, and any previous vaccine reactions
  • Remember that clinical trials and post-market studies provide much stronger safety evidence than VAERS alone

For the most up-to-date safety information, consult the CDC's vaccine information pages or speak with a qualified healthcare professional.

More Resources

When Do Side Effects Start?
73% occur within 3 days of vaccination
Serious vs Non-Serious Outcomes
The full severity spectrum in VAERS
Report an Adverse Event
How to file a VAERS report
Our Methodology
How we process VAERS data

2026 Safety Monitoring Update

As of mid-2026, the HPV vaccine continues to be monitored through VAERS and complementary surveillance systems including the Vaccine Safety Datalink (VSD) and the Clinical Immunization Safety Assessment (CISA) project. No new safety signals have been identified in recent data that would change the established safety profile of this vaccine.

The HHS administration's announced development of AI-powered VAERS analysis tools may provide additional insights into HPV vaccine adverse event patterns. These tools aim to detect subtle signals that traditional statistical methods might miss, though their implementation timeline and methodology remain under development.

It's worth noting that VAERS reporting for routine vaccines like HPV has remained stable through the post-pandemic period. While COVID-19 vaccine reports surged and then declined, reporting patterns for established childhood and adult vaccines have been remarkably consistent, suggesting that the VAERS system continues to function as designed for ongoing safety surveillance.

Understanding VAERS Data for HPV

When interpreting VAERS data for HPV vaccines, several key principles apply:

  • Reports ≠ Causation: A VAERS report means an event occurred after vaccination. It does not establish that the vaccine caused the event. Many reported symptoms are common health occurrences that would happen regardless of vaccination.
  • No denominator: VAERS does not track the number of doses administered. Without knowing how many people received the vaccine, raw report counts cannot be used to calculate risk rates or compare safety across vaccines.
  • Co-administration: Many vaccines are given at the same visit. When a VAERS report lists multiple vaccines, it's impossible to determine which vaccine (if any) was responsible for the reported adverse event.
  • Reporting variability: Healthcare provider awareness, media attention, and public concern all influence how many reports are filed. Changes in report volume may reflect changes in reporting behavior rather than changes in actual safety.

How to Use This Data Responsibly

VAERS data is most useful as a starting point for conversation with your healthcare provider, not as a basis for medical decisions. If you're concerned about HPV vaccine side effects:

  • Discuss your specific risk factors with your doctor or pharmacist
  • Ask about the relative risks of the disease the vaccine prevents vs. the vaccine itself
  • Consider your age, health status, and any previous vaccine reactions
  • Remember that clinical trials and post-market studies provide much stronger safety evidence than VAERS alone

For the most up-to-date safety information, consult the CDC's vaccine information pages or speak with a qualified healthcare professional.

More Resources

When Do Side Effects Start?
73% occur within 3 days of vaccination
Serious vs Non-Serious Outcomes
The full severity spectrum in VAERS
Report an Adverse Event
How to file a VAERS report
Our Methodology
How we process VAERS data

More Side Effect Guides

All Vaccine Side Effects
Overview across all vaccines
COVID-19 Side Effects
1.1M+ reports analyzed
Full Dashboard
All 104 vaccines compared