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Data source: VAERS (Vaccine Adverse Event Reporting System)

Data through 2026 · Updated quarterly

Built by TheDataProject.ai · © 2026 VaccineWatch

Important: VAERS accepts reports of adverse events following vaccination. For any given report, there is no certainty that the reported event was caused by the vaccine. Reports may contain information that is incomplete, inaccurate, coincidental, or unverifiable. Most reports to VAERS are voluntary, which means they are subject to biases. This data cannot be used to determine if vaccines cause or contribute to adverse events.

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Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.

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  4. Systemic inflammatory response syndrome
COVID-19 Vaccine×Systemic inflammatory response syndrome

Systemic inflammatory response syndrome Reports for COVID-19 Vaccine

#948 most reported symptom for this vaccine

406
Reports
31
Deaths
336
Hospitalizations
7.64
Mortality Rate
%
82.8
Hosp. Rate
%

Systemic inflammatory response syndrome and COVID-19 Vaccine

Systemic inflammatory response syndrome has been reported 406 times in association with COVID-19 Vaccine vaccination in VAERS. This represents 0.0% of all 1,121,388 reports for this vaccine.

Among these reports, 31 mentioned death (7.64%) and 336 involved hospitalization (82.8%).

Systemic inflammatory response syndrome is the #948 most frequently reported symptom for COVID-19 Vaccine out of 9223 total symptoms.

Disclaimer: VAERS reports describe events that occurred after vaccination but do not establish that the vaccine caused the event. Many reported symptoms may be coincidental or related to underlying conditions.

What This Means

Seeing 406 reports of Systemic inflammatory response syndrome after COVID-19 Vaccine vaccination may seem alarming, but context is critical. With 1,121,388 total reports for this vaccine (representing many millions of doses), Systemic inflammatory response syndrome appears in only 0.0% of reports.

The 7.64% mortality rate among these reports is elevated, but this reflects the severity of the condition itself rather than vaccine causation.

Important Context

•Association, not causation: These reports show Systemic inflammatory response syndrome occurred after vaccination, not that the vaccine caused it.
•Background rates: Systemic inflammatory response syndrome may occur naturally at baseline rates in the population, unrelated to vaccination.
•Anyone can report: VAERS accepts reports from anyone — patients, parents, healthcare providers — without requiring medical verification.
•Denominator missing: VAERS counts reports, not rates per dose. Without knowing how many doses were given, raw counts can be misleading. Learn more →

Similarly Ranked Symptoms

Visual field defect407 reportsGingival bleeding406 reportsCrohn's disease405 reportsTroponin I normal403 reports

Quick Facts

Reports:406
Deaths:31
Hospitalizations:336
% of Vaccine:0.0%
Rank:#948 of 9223

Related Pages

COVID-19 Vaccine OverviewSystemic inflammatory response syndrome (All Vaccines)Why Raw Numbers MisleadTop Symptoms Analysis

Data Source

This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.