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Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.

Depression

3,322 total reports18.0% serious outcomes
3,322
Total Reports
40
Deaths
557
Hospitalizations
18
Severity Rate
% serious outcomes

About Depression Reports

Depression has been reported 3,322 times in VAERS from 1990 to 2026.

Of these reports, 40 were associated with death (1.20%) and 557 involved hospitalization.

The overall serious outcome rate (death or hospitalization) for reports mentioning Depression is 18.0%.

Understanding Depression in VAERS

Temporal association only: These reports show Depression occurred after vaccination, not necessarily because of vaccination.
Background rates matter: Many symptoms occur naturally at baseline rates in the population, unrelated to vaccination.
Reporting variability: Medical terminology may be used differently by various healthcare providers and over time.
Investigation needed: High-frequency reports may trigger further epidemiological studies to determine causation.

What This Data Shows

Most Associated Vaccines: The vaccines most frequently mentioned in reports with Depression. This may reflect usage patterns, not causation.
Severity Patterns: The percentage of reports that involve serious outcomes can help prioritize safety investigations.
Reporting Trends: Changes in reporting frequency over time may reflect increased awareness, media attention, or actual safety signals.

Quick Facts

Reports:3,322
Deaths:40
Hospitalizations:557
Mortality Rate:1.20%
Severity Rate:18.0%

Data Source

This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.